Web3 okt. 2024 · HOXB7 is often overexpressed in breast cancer cells and found to relate to poor prognosis. The search for the HOXB7 targets, as a transcription factor, has led to molecules involved in regulating cell proliferation, migration, invasion, and processes such as angiogenesis and therapy resistance. However, the specific targets affected by the … http://www.cancerindex.org/geneweb//HOXB7.htm
Cancers Free Full-Text Functional Genomic Analysis of Breast Cancer …
WebE2F activity is frequently controlled via the retinoblastoma protein (pRb), cyclins, p53 and the ubiquitin-proteasome pathway. Additionally, genetic or epigenetic changes result in the deregulation of E2F family genes expression altering S phase entry and apoptosis, an important hallmark for the onset and development of cancer. WebHomeobox B7 (HOXB7) has a role in many cellular processes. It has been shown to be expressed in hepatocellular carcinoma. It may also have a role in cell migration and invasion in gastric cancer. This transcription factor is vital for tissue differentiation and embryogenesis.HOXB7 may be a potential drug target in various cancers. new greek bothell homes for sale
Showing papers by "Francesco Blasi published in 2008"
Web7 apr. 2011 · This study was to investigate the clinicopathologic significance and potential role of HOXB7 in the development and progression of colorectal cancer (CRC). Experimental design The relationship between HOXB7 expression and clinical characteristics of CRC was analyzed in 224 paraffin-embedded archived CRC … Web1 jun. 2024 · Some studies have found that HOXB7 was overexpressed in both cancer cell lines and cancer tissues of gastric cancer patients. It has been reported that … Web16 sep. 2024 · In A375 and 397 human melanoma cells, PBX1 interacts with HoxB7, and PBX1 knockdown decreases pro-angiogenic factors angiopoietin-2 (Ang-2) and matrix metalloprotease 9 (MMP9) at both mRNA and protein levels . The PBX1 silencing … interval recording form